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Aron Goldhirsch Selected Research

Letrozole (Femara)

2/2021Cumulative incidence of cardiovascular events under tamoxifen and letrozole alone and in sequence: a report from the BIG 1-98 trial.
1/2021Genomic Aberrations and Late Recurrence in Postmenopausal Women with Hormone Receptor-positive Early Breast Cancer: Results from the SOLE Trial.
3/2020Correction: Quality of life under extended continuous versus intermittent adjuvant letrozole in lymph node-positive, early breast cancer patients: the SOLE randomised phase 3 trial.
10/2019Neoadjuvant Degarelix Versus Triptorelin in Premenopausal Patients Who Receive Letrozole for Locally Advanced Endocrine-Responsive Breast Cancer: A Randomized Phase II Trial.
10/2019Adjuvant Letrozole and Tamoxifen Alone or Sequentially for Postmenopausal Women With Hormone Receptor-Positive Breast Cancer: Long-Term Follow-Up of the BIG 1-98 Trial.
1/2019Quality of life under extended continuous versus intermittent adjuvant letrozole in lymph node-positive, early breast cancer patients: the SOLE randomised phase 3 trial.
1/2018Extended adjuvant intermittent letrozole versus continuous letrozole in postmenopausal women with breast cancer (SOLE): a multicentre, open-label, randomised, phase 3 trial.
1/2016Treatment Adherence and Its Impact on Disease-Free Survival in the Breast International Group 1-98 Trial of Tamoxifen and Letrozole, Alone and in Sequence.
12/2015ESR1 and ESR2 polymorphisms in the BIG 1-98 trial comparing adjuvant letrozole versus tamoxifen or their sequence for early breast cancer.
10/2015Intermittent Letrozole Administration as Adjuvant Endocrine Therapy for Postmenopausal Women With Hormone Receptor-Positive Early Breast Cancer: A Biologic Study.
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Aron Goldhirsch Research Topics

Disease

182Breast Neoplasms (Breast Cancer)
10/2021 - 09/2002
89Neoplasms (Cancer)
10/2021 - 03/2003
9Neoplasm Metastasis (Metastasis)
11/2016 - 09/2002
8Disease Progression
09/2019 - 06/2004
6Triple Negative Breast Neoplasms
01/2016 - 09/2008
5Cardiovascular Diseases (Cardiovascular Disease)
02/2021 - 06/2003
4Lobular Carcinoma
10/2021 - 10/2009
4Hypertension (High Blood Pressure)
01/2018 - 12/2007
4Hypercholesterolemia
04/2017 - 12/2005
4Ductal Carcinoma
09/2015 - 07/2009
3Melanoma (Melanoma, Malignant)
01/2018 - 08/2013
3Arthralgia (Joint Pain)
01/2018 - 02/2007
3Hot Flashes
11/2016 - 01/2007
3Cardiotoxicity
12/2010 - 10/2005
3Bone Fractures (Bone Fracture)
04/2008 - 06/2003
3Amenorrhea
07/2007 - 03/2006
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2019 - 01/2018
2Carcinoma (Carcinomatosis)
04/2013 - 09/2003
2Inflammatory Breast Neoplasms
12/2010 - 09/2008
2Heart Failure
09/2010 - 02/2007
2Venous Thromboembolism
10/2007 - 10/2005
2Uterine Hemorrhage (Uterine Bleeding)
02/2007 - 12/2005
2Endometrial Neoplasms (Endometrial Cancer)
12/2005 - 12/2004
2Thromboembolism
12/2005 - 06/2003
1Myocardial Ischemia (Ischemic Heart Diseases)
02/2021
1Lung Neoplasms (Lung Cancer)
01/2019

Drug/Important Bio-Agent (IBA)

53Hormones (Hormone)IBA
10/2021 - 06/2004
45TamoxifenFDA LinkGeneric
02/2021 - 06/2003
39Estrogen ReceptorsIBA
01/2020 - 03/2003
32Letrozole (Femara)FDA LinkGeneric
02/2021 - 12/2005
27Progesterone Receptors (Progesterone Receptor)IBA
01/2021 - 03/2003
20Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2017 - 04/2003
18Biological ProductsIBA
10/2021 - 06/2004
18Trastuzumab (Herceptin)FDA Link
09/2019 - 10/2005
18Fluorouracil (Carac)FDA LinkGeneric
11/2016 - 04/2003
13Methotrexate (Mexate)FDA LinkGeneric
11/2016 - 09/2002
12Aromatase InhibitorsIBA
02/2021 - 12/2005
12Estrogens (Estrogen)FDA Link
12/2015 - 06/2004
11Cisplatin (Platino)FDA LinkGeneric
08/2015 - 11/2006
11SteroidsIBA
08/2013 - 10/2004
9Phenobarbital (Luminal)FDA Link
10/2021 - 04/2012
9exemestane (Aromasin)FDA Link
01/2020 - 09/2003
9human ERBB2 proteinIBA
10/2016 - 06/2010
8Capecitabine (Xeloda)FDA Link
01/2017 - 04/2002
8Epirubicin (Ellence)FDA LinkGeneric
08/2015 - 01/2006
7ErbB Receptors (EGF Receptor)IBA
10/2019 - 11/2006
6Biomarkers (Surrogate Marker)IBA
01/2021 - 03/2003
6Monoclonal AntibodiesIBA
01/2017 - 10/2005
6Bevacizumab (Avastin)FDA Link
06/2015 - 10/2008
5Vinorelbine (Navelbine)FDA LinkGeneric
01/2017 - 02/2006
5AnthracyclinesIBA
08/2015 - 01/2006
5ProgesteroneFDA LinkGeneric
08/2015 - 09/2007
5Cancer VaccinesIBA
02/2014 - 09/2007
5VaccinesIBA
01/2014 - 09/2007
4Gonadotropin-Releasing Hormone (GnRH)FDA Link
10/2019 - 12/2003
4DNA (Deoxyribonucleic Acid)IBA
12/2015 - 06/2010
4Pharmaceutical PreparationsIBA
03/2015 - 11/2007
4Neoplasm Antigens (Tumor Antigens)IBA
02/2014 - 12/2007
4AntigensIBA
02/2014 - 10/2009
4liposomal doxorubicin (Doxil)FDA Link
04/2013 - 12/2010
3Triptorelin Pamoate (Trelstar)FDA Link
10/2019 - 04/2010
3Paclitaxel (Taxol)FDA LinkGeneric
08/2015 - 09/2008
31-dodecylpyridoxal (PLD)IBA
04/2013 - 12/2010
3Fulvestrant (Faslodex)FDA Link
10/2012 - 11/2007
3Erlotinib Hydrochloride (CP 358,774)FDA Link
06/2012 - 11/2006
3Tyrosine Kinase InhibitorsIBA
02/2012 - 11/2006
3Doxorubicin (Adriamycin)FDA LinkGeneric
12/2010 - 01/2008
3Leucovorin (Folinic Acid)FDA Link
12/2008 - 09/2002
3Goserelin (Zoladex)FDA Link
03/2008 - 12/2003
2Immune Checkpoint InhibitorsIBA
01/2018 - 03/2014
2CholesterolIBA
04/2017 - 06/2003
2Estrogen Receptor alphaIBA
11/2016 - 12/2015
2Epidermal Growth Factor (EGF)IBA
04/2016 - 10/2012
2Lapatinib (GW572016)FDA Link
04/2016 - 02/2012
2Docetaxel (Taxotere)FDA Link
08/2015 - 01/2008
2LigandsIBA
02/2015 - 03/2006
2Cell-Free Nucleic AcidsIBA
06/2014 - 06/2004
2collagen type I trimeric cross-linked peptideIBA
04/2014 - 06/2003
2AntibodiesIBA
02/2014 - 08/2013
2Proteins (Proteins, Gene)FDA Link
11/2012 - 04/2003
2Anastrozole (Arimidex)FDA LinkGeneric
10/2012 - 06/2004
2Hemoglobins (Hemoglobin)IBA
06/2012 - 01/2008
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2009 - 06/2004
2taxaneIBA
03/2009 - 01/2008
2Toremifene (Fareston)FDA Link
02/2006 - 12/2004
1antineoplaston A10 (A 10)IBA
01/2020
1acetyl- 2- naphthylalanyl- 3- chlorophenylalanyl- 1- oxohexadecyl- seryl- 4- aminophenylalanyl(hydroorotyl)- 4- aminophenylalanyl(carbamoyl)- leucyl- ILys- prolyl- alaninamideFDA Link
10/2019
1sparfosic acid (PALA)IBA
01/2019
1TOR Serine-Threonine KinasesIBA
01/2018

Therapy/Procedure

89Therapeutics
10/2021 - 01/2003
73Drug Therapy (Chemotherapy)
09/2019 - 09/2002
23Adjuvant Chemotherapy
01/2017 - 04/2003
11Neoadjuvant Therapy
11/2014 - 05/2005
9Immunotherapy
01/2019 - 09/2007
7Radiotherapy
01/2018 - 05/2007
5Mastectomy (Mammectomy)
01/2018 - 02/2009
3Segmental Mastectomy (Lumpectomy)
10/2016 - 05/2005
3Mammaplasty (Breast Reconstruction)
10/2015 - 08/2011
3Catheters
10/2007 - 10/2005
2Cell- and Tissue-Based Therapy (Cell Therapy)
02/2014 - 08/2013